COMPLETE THE CURE™
With the development and rise of gene editing, CRISPR-Cas9, technologies, humanity has a real opportunity to cure virtually all genetic diseases, such as Duchenne muscular dystrophy. Gene editing technology has given us the ability to rewrite our DNA and correct faulty DNA, like mutations that cause diseases. The applications for gene editing to improve the world are nearly endless and we want to be the champion of advancing gene editing to human trials for people with Duchenne. It could be said that the current state of gene editing technology, CRISPR-Cas9, is the tool to cure Duchenne that needs to be perfected before it can be applied in humans. More scientific studies need to be done to perfect this tool, CRISPR-Cas9, and that is why we so passionately say we need to: Complete The Cure™.
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CRISPR enables scientists to accomplish such feats by finding and fixing single incorrect letters of DNA out of the 3.2 billion letters that make up the human genome, but it can be used to perform even more complex modifications. Researchers have corrected the DNA mistakes that causes Duchenne muscular dystrophy by snipping out only the damaged region of the mutated gene, leaving the rest intact.
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- Jennifer Doudna, PhD,
Discovered CRISPR-Cas9 and is internationally recognized as the leading expert on CRISPR biology
CRISPR-Cas9
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I am betting my life on it. I mean that in the most literal sense, that’s how much I believe in it.
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- Elijah Stacy
Founder of Destroy Duchenne and patient with DMD
Gene editing is the future, now
In 2015 a little girl named Layla Richards became the first human to have their life saved by therapeutic gene editing. Layla, a baby at the time, was suffering from lymphoblastic leukemia, the most common form of childhood leukemia. She became so weak that doctors suggested end-of-life care to the parents, but the parents continued to fight and then they were presented with an experimental trial. This therapy had previously only been tested on mice in the laboratory before they tried it on Layla. Fortunately, gene editing therapy worked and saved Layla’s life. This has become a widely used case to demonstrate the potential gene editing therapies has to cure diseases.
The opportunity is now
By supporting Destroy Duchenne, you are directly playing a role in advancing gene editing technologies. You automatically become a difference maker. Think about it, you will be a part of making the future of medicine a reality practice that saves lives. You will be someone who is changing the world. There’s plenty of other ways to spend your money, but this is one way that will impact the world.
It just makes sense to support someone who believes in something so much that they’re betting their life on it, literally.